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Fig. 1 | Molecular Brain

Fig. 1

From: Synaptopodin is required for long-term depression at Schaffer collateral-CA1 synapses

Fig. 1

SPKO mice show a deficit of LFS-LTD and HFS-LTP. (A) Diagram showing the positions of stimulating and recording electrodes at the Sc-CA1 synapses. (B) BCM curves in WT and SPKO for 2, 10 and 100 Hz stimulation frequency. (C) (Left) Time course of normalized fEPSP in WT and SPKO following 2 Hz (900 pulses) stimulation. (Right) Quantification of average synaptic modification in the last 10 min of the recording. (D) (Left) Time course of normalized fEPSP in WT and SPKO following 10 Hz (900 pulses) stimulation. (Right) Quantification of average synaptic modification in the last 10 min of the recording. (E) (Left) Time course of normalized fEPSP in WT and SPKO following 100 Hz (900 pulses) stimulation. (Right) Quantification of average synaptic modification in the last 10 min of the recording

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Molecular Brain

ISSN: 1756-6606