Figure 2

Behavioral analyses of mito-mice before and after cognitive analyses. To examine behavioral performances in the low group (black), and high (gray) group, three kinds of traditional behavioral tests were performed before and after cognitive analyses. (A) Elevated plus maze test. There was no difference in phenotypes of anxiety-related behavior between the low and high groups at the two time points (number of total entries: P = 0.6823 in before, P = 0.9775 in after; entries onto open arms: P = 0.4360 in before, P = 0.8226 in after; time spent on open arms: P = 0.7157 in before, P = 0.6756 in after). (B) Light-dark transition test. There was no difference in phenotypes of anxiety-related behavior between the low and high groups at the two time points (time spent in light side: P = 0.9125 in before, P = 0.0625 in after; total number of transitions: P = 0.4083 in before, P = 0.4569 in after; first latency to enter light side: P = 0.3812 in before, P = 0.9798 in after). (C) Porsolt forced-swim test. There was no difference in phenotypes of depressant-related behaviors between the low and high groups at the two time points (before: P = 0.1479 in day 1, P = 0.0526 in day 2; after: P = 0.9900 in day 1, P = 0.3132 in day 2). All values are means ± SE.