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Figure 4 | Molecular Brain

Figure 4

From: A novel mechanism of hippocampal LTD involving muscarinic receptor-triggered interactions between AMPARs, GRIP and liprin-α

Figure 4

Interaction between liprin α and GRIP is required for mAChR-LTD. (A) Intracellular infusion of the C terminal fragment of liprin α (TVRTYSC) prevents induction of mAChR-LTD (n = 6). (B) A control peptide (TVRTASC) has no affect on mAChR-LTD (n = 5). (C) TVRTYSC (n = 7) has no effect on mGluR-LTD. (D) TVRTASC (n = 8) has no effect on mGluR-LTD. (E) TVRTYSC (n = 6) has no effect on NMDAR-LTD. (F) TVRTASC (n = 6) has no effect on NMDAR-LTD.

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