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Figure 1 | Molecular Brain

Figure 1

From: Frontotemporal dementia and amyotrophic lateral sclerosis-associated disease protein TDP-43 promotes dendritic branching

Figure 1

dTDP-43 promotes dendritic branching in Drosophila. (A) Schematic representation of the domain structure of dTDP-43. RRM: RNA recognition motif. GRR: glycine-rich region. (B) Dendritic phenotypes of ddaE and ddaF sensory neurons in the A3 segment of third instar larvae that are either wildtype (a) or overexpress dTDP-43 with the Gal4221 driver (b). (C) Quantification of dendritic ends of ddaE and ddaF neurons. The number of neurons examined is indicated in each column. Values are mean ± SEM. ***P < 0.001.

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Molecular Brain

ISSN: 1756-6606