Figure 1From: Synaptosomal-associated protein 25 mutation induces immaturity of the dentate granule cells of adult miceDecrease in adult hippocampal neurogenesis in mutant mice. (A, B) Cell proliferation was analyzed using BrdU staining (n = 6 mice each). Arrowheads indicate BrdU-positive cells. (C, D) Images of doublecortin (DCX)-positive cells (arrowheads) in the GCL are shown. ML, molecular layer. SGZ, subgranular zone. HL, hilus. (E) Quantification of DCX-positive cell numbers in the GCL (n = 4 mice each). (F) The positions of DCX-positive cells are shown as relative values between the subgranular layer (SGL; 0) and the border with the molecular layer (ML; 1) (n = 4 mice each).Back to article page