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Table 1 Spontaneous activities counts of mice in the open field test

From: Effects of NB001 and gabapentin on irritable bowel syndrome-induced behavioral anxiety and spontaneous pain

Counts

Day

Intracolonic saline

Intracolonic zymosan

P

Vertical

1

800.5 ± 63.8

492.2 ± 42.4

< 0.001

 

7

1055.3 ± 72.8

498.0 ± 51.8

< 0.001

 

14

976.7 ± 50.6

450.5 ± 53.2

< 0.001

 

28

1026.8 ± 58.6

438.2 ± 49.9

< 0.001

Ambulatory

1

1979.3 ± 158.2

1404.0 ± 133.3

< 0.05

 

7

2374.7 ± 155.7

1343.0 ± 152.5

< 0.001

 

14

2336.7 ± 172.2

1155.0 ± 117.4

< 0.001

 

28

2448.3 ± 161.9

1279.7 ± 147.4

< 0.001

Stereotypic

1

5011.3 ± 254.8,

4094.3 ± 257.1

< 0.05

 

7

4961.3 ± 260.0

3024.8 ± 214.6

< 0.001

 

14

5206.7 ± 265.7

3124.8 ± 289.2

< 0.001

 

28

4862.7 ± 259.3

2970.2 ± 218.7

< 0.001

Jump

1

120.8 ± 13.9

60.7 ± 10.6

< 0.01

 

7

129.5 ± 10.9

62.7 ± 9.7

< 0.001

 

14

122.5 ± 14.0

67.0 ± 8.5

< 0.01

 

28

117.8 ± 12.3

64.7 ± 11.5

< 0.01

  1. P: in comparison with saline intracolonic treated group; n = 6 mice per group.