Identification of plasma microRNAs as a biomarker of sporadic Amyotrophic Lateral Sclerosis

Table 2 Up- or down- regulated miRNAs using microarray analysis and extraction of an internal control

Differential expression type	MiRNA name	Fold change	p value
Differential expression type	MiRNA name	Fold change	Student t-test	Wilcoxon sum ranked test
Up-regulated	hsa-miR-4258	1.109	<0.0001*	0.0001*
	hsa-miR-663b	1.117	0.0004*	0.0017*
	hsa-miR-4649-5p	1.045	0.0659	0.179
Down-regulated	hsa-miR-26b-5p	0.374	<0.0001*	0.0001*
	hsa-miR-4299	0.435	0.0001*	0.0006*
	hsa-let-7f-5p	0.464	<0.0001*	0.0002*
	hsa-miR-4419a	0.464	0.0001*	0.0002*
	hsa-miR-3187-5p	0.485	0.0002*	0.0001*
	hsa-miR-4496	0.495	0.0003*	0.0011*
Candidates of Internal control	hsa-miR-4516	0.999	0.9340

ISSN: 1756-6606