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Fig. 8 | Molecular Brain

Fig. 8

From: NMDA receptor agonists reverse impaired psychomotor and cognitive functions associated with hippocampal Hbegf-deficiency in mice

Fig. 8

Neurobiological effects of D-cycloserine and nefiracetam in Hbegf cKO mice. a-c, Effects of D-cycloserine and nefiracetam on the decrease in levels of p-ERK1, p-ERK2, p-NR1, total NR1, NR2B and PSD-95. Schedule of drug treatments were the same as in Fig. 6a. Results represent typical pictures of western blot analysis: (a), and quantitative comparisons: (b). n = 5 (all groups). Values are the means ± s.e.m. Typical pERK1/2-like immunohistochemical pictures in the hippocampus: (c)

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Molecular Brain

ISSN: 1756-6606