Amyotrophic lateral sclerosis patient iPSC-derived astrocytes impair autophagy via non-cell autonomous mechanisms

Table 1 Details of patient and control iPSC lines used in this study

iPSC line	Age	Sex	Patient status	Reprogramming method
iPS04c3	20	Male	Control	Lentiviral
iPSC1cx1	57	Female	Control	Episomal
iPSC3c2	47	Female	Control	Episomal
iPS21c1	45	Male	ALS C9ORF72 R.E.	Lentiviral
iPS21cx	45	Male	ALS C9ORF72 R.E.	Lentiviral
iPS24c1	61	Male	ALS, C9ORF72 negative	Episomal
iPS31c8	57	Female	ALS C9ORF72 R.E.	Lentiviral

Two patients harbor a G₄C₂ hexanucleotide repeat expansion in the C9ORF72 gene

ISSN: 1756-6606