Fig. 1From: Cortical pain induced by optogenetic cortical spreading depression: from whole brain activity mappingCSD waveform and cerebral blood flow changes. A Electrophysiological recordings showed a broad negative wave were recorded in motor cortex, which was consistent with the characteristics of CSD waveform. B Representative blood flow perfusion from the ipsilateral cortex, consisting of the initial hypoperfusion followed by a transient recovery of perfusion and a long-lasting oligemia. The zigzag line represented the light stimulationBack to article page