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Fig. 8 | Molecular Brain

Fig. 8

From: C1ql1-Bai3 signaling is necessary for climbing fiber synapse formation in mature Purkinje cells in coordination with neuronal activity

Fig. 8

Proposed model for re-innervation of mature PCs by excess CFs through C1ql1-Bai3 signaling

Increased C1ql1-Bai3 signaling induces re-innervation of mature PCs by excess CFs. These new CF inputs, derived from transverse CF branches of neighboring PCs, synapse onto the distal dendrites of PCs (left). Neuronal activity of both CFs and PCs is required for C1ql1-Bai3 signaling to induce surplus CFs (right)

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Molecular Brain

ISSN: 1756-6606