Fig. 2

Rab11a expression level is correlated with the process of inflammatory pain

A, the experimental procedure. B, the PWMT in sham and CFA groups (n = 6 mice in each group, Two-Way ANOVA followed by Tukey’s post-hoc test, F_(1,4) = 139.5, P = 0.0003). C, immunofluorescent samples showing the Rab11a positive cells expressing Fos protein in lamina I-IV of the spinal cord after CFA injection. D, the number of Rab11a-Fos positive cells in lamina I-IV (n = 3 mice in each group, One-Way ANOVA followed by Tukey’s post-hoc test, I: F_(3,8) = 51.92, P < 0.0001; II: F_(3,8) = 6.257, P = 0.0171; III: F_(3,8) = 7.903, P = 0.0089). E, samples and quantitative analysis of Rab11a expression levels via western blotting (n = 3 mice in each group, One-Way ANOVA followed by Tukey’s post-hoc test, F_(3,8) = 30.60, P < 0.0001). *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001. Bars equal to100 µm in C