Fig. 5
Rab11a-shRNA decreases the excitation of SDH neurons
A, Representative traces of spike numbers in sham + scrambled-shRNA (sham + scramble), sham + Rab11a-shRNA (sham + shRNA), CFA + scrambled-shRNA (CFA + scramble), and CFA + Rab11a-shRNA (CFA + shRNA) groups. B, Averaged spike numbers induced by step currents injection (300 ms, 0-200 pA) (Two way ANOVA followed by Turkey post hoc test, F = P=, vs. ** P; vs. ### P). C, Representative traces of the first AP of neurons in SDH induced by + 5 pA step depolarizing current intracellular injections. D-F, the rheobase current (D), input resistance (E) and resting membrane potential (F) in sham + scramble (n = 15 cells of 4 mice), sham + shRNA (n = 12 cells of 3 mice), CFA + scramble (n = 9 cells of 3 mice), and CFA + shRNA (n = 15 cells of 4 mice) groups (One-Way ANOVA followed by Tukey’s post-hoc test. F(3,47) = 3.012, P = 0.0393 (D); F(3,36) = 5.689, P = 0.0027 (E); F(3,51) = 0.825, P = 0.4861 (F). *P < 0.05, **P < 0.01)