Fig. 1

Lipid-related signal disorders in postmenopausal women and in women with cognitive impairment. The sample information and the sequencing results of random needle aspiration samples from normal breast tissue of premenopausal (n = 8) and postmenopausal (n = 10) women were extracted and analyzed from the GSE36318 data set. A The groups were defined using GEO2R, and the sequencing data for the samples were standardized. B Ages were extracted from sample information, and histograms were drawn to analyze differences between premenopausal (n = 8) and postmenopausal (n = 10) women. C GEO2R was used to analyze genes that were differentially expressed between premenopausal and postmenopausal women. KEGG signal enrichment analysis was performed with differentially expressed genes between the two groups, and a bubble diagram was drawn. D GO-MP signal enrichment analysis was performed with differentially expressed genes between the premenopausal and postmenopausal women, and a loop graph was drawn. The sample information and the sequencing results of hippocampal tissue from female incipient AD patients (n = 5) and severe AD (n = 5) patients were extracted and analyzed from the GSE1297 data set. E The groups were defined using GEO2R, and the sequencing data for the samples were standardized. F Ages were extracted from sample information, and histograms were drawn to analyze differences between female incipient AD patients and severe AD patients. G Mini-mental state examination results were extracted from sample information, and a histogram was drawn to analyze the differences between female incipient AD patients and severe AD patients. H GEO2R was used to analyze genes that were differentially expressed between female incipient AD patients and severe AD patients. KEGG signal enrichment analysis was performed with differentially expressed genes between the two groups, and a bubble diagram was drawn. I GO-MP signal enrichment analysis was performed with differentially expressed genes between the female incipient AD patients and severe AD patients, and a loop graph was drawn