Deficit of long-term memory retention in sdy mice. (A) Latency to reach the target hole (up), numbers of errors (middle) and distance to reach the target hole (bottom) across training were recorded. Data were analyzed by two-way repeated measures ANOVA. Data are presented as averages of 3 trials. (B) Time spent around each hole in the probe trial conducted 24 hours after last training. (C) Time spent around each hole in the probe trial conducted 7 days after last training. Time spent around target hole and holes adjacent to the target were compared by paired t-test.