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Figure 5 | Molecular Brain

Figure 5

From: Environmental neurotoxin dieldrin induces apoptosis via caspase-3-dependent proteolytic activation of protein kinase C delta (PKCdelta): Implications for neurodegeneration in Parkinson's disease

Figure 5

Dieldrin-induced apoptosis in N27 cells. N27 cells (~1 × 106 cells/ml) were treated with 100 μM dieldrin for 3 hr, and apoptotic cells were detected by flow cytometry as described in "Materials and Methods." Dual staining of cells with annexin-V-FITC and propidium iodide enabled categorization of cells into four regions (A, B, C, and D). Region A was apoptotic cells, B was apoptotic and necrotic cells, C was live or healthy cells, and D was necrotic cells. The experiment was repeated three times and data represent the average of each region.

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