Figure 3

Normal memory ability of CS-KO mice in eight-arm radial maze and Barnes maze. In the eight-arm radial maze (A), we could not detect a significant difference between genotypes in the different arm choices in first 8 entries (Aa), in the number of revisiting errors (Ab), or in latency to take all the pellets (Ac). The bold horizontal bars in graph Aa-Ac indicate the delay task sessions (Delay duration: 30, 120, and 300 sec from the left respectively). In Barnes maze (B), we could not detect a significant difference between genotypes in either the latency to reach the correct hole above the escape box (Ba) or in the number of trials to the first entry into the escape box (Bb) of acquisition trials. In probe trial (transfer test) performance on day 10 (Bc), CS-KO mice appeared normal as regards the time spent around each escape hole. Data are expressed as mean ± S.E.M.