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Figure 2 | Molecular Brain

Figure 2

From: Induction- and conditioning-protocol dependent involvement of NR2B-containing NMDA receptors in synaptic potentiation and contextual fear memory in the hippocampal CA1 region of rats

Figure 2

NR2B-NMDARs are not required for LTP induced by pairing protocol in area CA1. A. Schematic diagram of the pairing protocol. B. Pairing protocol, as indicated by the arrow, induced a significant LTP in CA1 pyramidal neurons (n = 6). Sample traces of EPSC are the averages of 7 consecutive responses recorded during 5–10 min and 25–30 min, respectively. C. Bath application of Ro25-6981 (0.5 μM) had no effect on the LTP (n = 5). D. Histogram showing the effect of Ro25-6981 on the LTP. p > 0.05 vs. control.

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