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Figure 1 | Molecular Brain

Figure 1

From: Effect of ablated hippocampal neurogenesis on the formation and extinction of contextual fear memory

Figure 1

MAM treatments reduced hippocampal neurogenesis but did not affect gross morphology. (A) Representative images show the dentate gyrus of mice that were injected with MAM for 2 weeks. Doses of MAM are indicated in each image. Cells were labeled with BrdU (red) and DAPI (blue). Upper left: vehicle (Veh). Upper right: 1 mg/kg. Lower left: 2.5 mg/kg. Lower right: 5 mg/kg. Scale bar, 100 μm. (B) Total number of BrdU+ cells in dentate gyrus. Three mice were used for analysis. Note that two of the three mice died during 5 mg/kg MAM injection. *, p < 0.05; **, p < 0.01 compared with vehicle. Dentate gyrus (D.G).

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