Figure 1From: Effect of ablated hippocampal neurogenesis on the formation and extinction of contextual fear memoryMAM treatments reduced hippocampal neurogenesis but did not affect gross morphology. (A) Representative images show the dentate gyrus of mice that were injected with MAM for 2 weeks. Doses of MAM are indicated in each image. Cells were labeled with BrdU (red) and DAPI (blue). Upper left: vehicle (Veh). Upper right: 1 mg/kg. Lower left: 2.5 mg/kg. Lower right: 5 mg/kg. Scale bar, 100 μm. (B) Total number of BrdU+ cells in dentate gyrus. Three mice were used for analysis. Note that two of the three mice died during 5 mg/kg MAM injection. *, p < 0.05; **, p < 0.01 compared with vehicle. Dentate gyrus (D.G).Back to article page