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Figure 4 | Molecular Brain

Figure 4

From: Cocaine induces cell death and activates the transcription nuclear factor kappa-b in pc12 cells

Figure 4

Effect of PDTC, Sodium Salicilate and SCH23390 on cocaine-Induced toxicity in PC12 Cells (A and C: LDH release assay; B and D: MTT reduction assay). PC12 cells were pre-treated for 20 min with various concentrations of PDTC, Sodium Salicilate or SCH23390 prior to cocaine (1 mM, 6 hours) treatment. Cell viability was estimated by MTT reduction (570 nm) and LDH release (490 nm) assays. Results are expressed as mean + S.E.M. from three individual experiments. * p < 0.05 vs PBS and # p < 0.05 vs COC (cocaine) (one-way ANOVA followed by Newman-Keuls test)

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