Skip to main content
Figure 5 | Molecular Brain

Figure 5

From: Frontotemporal dementia and amyotrophic lateral sclerosis-associated disease protein TDP-43 promotes dendritic branching

Figure 5

Generation of transgenic flies that express wildtype and mutant hTDP-43. (A) Schematic representations of dTDP-43 and hTDP-43 and the positions of ALS-associated point mutations. RRM: RNA recognition motif. GRR: glycine-rich region. (B) Western blot analysis of the levels of wildtype or mutant hTDP-43 expressed in the eye with the GMR-Gal4 driver. The dTDP-43 antibody did not recognize the hTDP-43 C-terminal fragment. The asterisk indicates a nonspecific band. Actin was used as the loading control.

Back to article page

Molecular Brain

ISSN: 1756-6606