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Figure 3 | Molecular Brain

Figure 3

From: Characterization of intracortical synaptic connections in the mouse anterior cingulate cortex using dual patch clamp recording

Figure 3

Inhibitory synaptic transmission in the ACC. ( A ) Diagram and sample traces of synaptic connections from interneurons to pyramidal neurons. Pre, action potential is induced in the presynaptic interneuron under current clamp. Post, outward uIPSCs is recorded in postsynaptic neuron under voltage clamp holding at 0 mV. Average, the trace of the average of 10 original traces. ( B ) Diagram and sample traces of synaptic connections from interneuron to interneuron. ( C ) Pooled data (open circle and triangle) and summarized results (bar graph) showing the amplitude of uIPSCs for In-Py and In-In. ( D-G ) Pooled data (open circle and triangle) and summarized results (bar graph) indicate the latency ( D ), rise time ( E ), decay time ( F ) and half-width ( G ) of uEPSCs for In-Py and In-In. Unitary IPSCs from In-In pairs have faster kinetics than those from In-Py pairs.

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