Table 1 Analysis of anxiety-like behavior in GSK-3α female KO mice
From: Abnormalities in brain structure and behavior in GSK-3alpha mutant mice
Parameters (Number) | WT (n = 7) females | KO (n = 9) females | WT (n = 14) males | KO (n = 13) males |
|---|---|---|---|---|
Passages (n) | 1.57 ± 0.94 | 3.11 ± 1.56 | 0.42 ± 0.23 | 1.23 ± 0.52 |
Risk assessment (n) | 3 ± 1.1 | 5 ± 1.21 | 4.57 ± 0.75 | 4.23 ± 0.58 |
Head dips (n) | 10 ± 2.1 | 7.44 ± 1.16 | 9.71 ± 1.93 | 11.54 ± 1.7 |
Total number | 58.14 ± 4.37 | 59.67 ± 3.2 | 54.21 ± 3.64 | 59 ± 4.64 |
Open (%) | 16.56 ± 2.8 | 10.91 ± 2.67 | 12.39 ± 2.6 | 15.51 ± 2.16 |
Centre (%) | 46.55 ± 1.34 | 45.18 ± 0.69 | 45.37 ± 0.98 | 44.31 ± 1.28 |
Closed (%) | 36.89 ± 2.78 | 43.91 ± 2.62 | 42.24 ± 2.34 | 40.17 ± 2.14 |
Parameters (Time) | WT (n = 7) females | KO (n = 9) females | WT (n = 14) males | KO (n = 13) males |
Open (%) | 5.5 ± 1.18 | 2.62 ± 0.81 * | 4.47 ± 1.04 | 5.7 ± 1.2 |
Centre (%) | 25.11 ± 2.21 | 20.08 ± 1.68 | 21.39 ± 1.43 | 20.26 ± 1.72 |
Closed (%) | 69.38 ± 3.14 | 77.3 ± 2.26 * | 74.13 ± 1.78 | 74.04 ± 2.5 |