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Table 2 Quantitative analysis of adult neurogenesis in SGZ 28 days after BrdU injection.

From: Tryptophan 2,3-dioxygenase is a key modulator of physiological neurogenesis and anxiety-related behavior in mice

 

NeuN +

TuJ1 +

NeuN+/BrdU+

TuJ1+/BrdU+

Tdo +/+

91.28 ± 1.30

2.75 ± 0.33

0.47 ± 0.12

0.64 ± 0.12

Tdo -/-

89.62 ± 0.87

5.16 ± 0.47*

1.14 ± 0.12*

1.00 ± 0.13*

  1. Cells positive for neural markers, alone and in combination with BrdU, are indicated as a percentage of total cells. Cells were counted in >3 matched sections from the DG of each mouse (n = 3 for each genotype). These data represent means ± S.E. *, p < 0.05 versus Tdo+/+ mice (ANOVA, Scheffe's post-hoc test).
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Molecular Brain

ISSN: 1756-6606