Figure 2
From: Rapid and Direct Transport of Cell Surface APP to the Lysosome defines a novel selective pathway
APP is preferential expressed in the lysosome in Cos7 cells. Cos7 cells were transiently co-transfected with the fluorescent -tagged APP and compartment marker proteins and imaged using laser scanning confocal microscopy. A. Cos7 cells were transiently co-transfected with βAPP-CFP (green) and the full-length APP-YFP (FL-APP) (red). B. Cos7 cells transiently co-transfected with βAPP-CFP or YFP (green) constructs along with fluorescent-tagged compartment markers (red) C. Cos7 cells were transiently co-transfected with βAPP-CFP (green) a constructs along with compartment markers as indicated (red). Scale Bar = 10 microns.