Figure 1From: A study of long-term potentiation in transgenic mice over-expressing mutant forms of both amyloid precursor protein and presenilin-1Plaques and elevated levels of Aβ(40) and Aβ(42) in DbTg (Tg) mice. (A) Example hippocampal slices from 14 month old animals, illustrating plaque formation in the Dbtg mice (brown) accompanied by astrocytosis (black). (B) Pooled data showing levels of Aβ(40) and Aβ(42) in Wt and DbTg mice.Back to article page