Figure 2

MK-801 injected snails do not exhibit ITM or LTM. A) MK-801 injection does not alter aerial respiratory behaviour. Snails were placed in hypoxic pond water and the mean (± SEM) total breathing time was calculated before (pre-obs) and 1 h (1 h post MK) and 24 h (24 h post MK) a after they were injected with MK-801 (0.1 mL of 150 μM). The injection of MK-801 1 h before the breathing observation session did not alter aerial respiratory behaviour (ANOVA_2,17 F = 0.8922, p > 0.05). B) MK-801 inhibits the formation of ITM when administered 1 hour prior to training (30' TS vs. 3 h MT, p = 0.2856, n = 20). C) LTM formation is also blocked by injecting animals with MK-801 prior to training (60' TS vs. 24 h MT p = 0.3555, n = 23).