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Figure 3 | Molecular Brain

Figure 3

From: Lack of interleukin-1 type 1 receptor enhances the accumulation of mutant huntingtin in the striatum and exacerbates the neurological phenotypes of Huntington's disease mice

Figure 3

Increased GFAP staining in the striatum of HD-IL1R-/- mice. (A) EM48 immunofluorescent staining of the brain cortex and striatum of HD-IL1R+/- and HD-IL1R-/- mice showing the selective increase of GFAP staining in the striatum of HD-IL1R-/- mice. (B) High-magnification micrographs (63×) showing reactive glial cells with intense GFAP (red) in neuronal cells that also display mutant htt staining (green) in the striatum. The nuclei (blue) were revealed by Hoechst dye staining.

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Molecular Brain

ISSN: 1756-6606