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Figure 3 | Molecular Brain

Figure 3

From: Nigrostriatal neuronal death following chronic dichlorvos exposure: crosstalk between mitochondrial impairments, α synuclein aggregation, oxidative damage and behavioral changes

Figure 3

Transmission electron micrograph of SN of rat brain regions showing the ultra structural changes of nucleus after chronic dichlorvos exposure.(A), Chromatin condensation and reduced cytoplasmic volume were observed in SN. Scale bars - 500 nm. (B&C) Relatively normal appearance of perinuclear cytoplasmic contents including mitochondria, endoplasmic reticulum and Golgi apparatus in control group. Dichlorvos exposed animals showed mitochondrial enlargement with more distorted cristae (thick arrow head) in the surrounding neuropil of neurons. CSN: substantia nigra; CCS: corpus striatum;DSN: Dichlorvos substantia nigra;DCS: Dichlorvos corpus striatum. Scale bar: 500 nm.

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