Figure 3
From: MATH5 controls the acquisition of multiple retinal cell fates
Fate conversion of Math5 -lineage cells in Math5 -null retinas. Adult retinal sections from the control and Math5-null mice were immunolabeled with cell type-specific markers (red) and anti-GFP (green). (A-D) Math5-lineage cone photoreceptors marked by RXRγ (arrows in A and B) are increased in number but the rod photoreceptors labeled by rhodopsin (arrows in C and D) are reduced in number in Math5-null retinas. (E-H) Among the Math5-lineage cells, BHLHB5+ (E, F) and GAD65+ (G, H) GABAergic amacrine cells (arrows) are reduced in number in the INL but are increased in the GCL of Math5-null retinas. (I, J) Calretinin+ amacrine subtypes (arrows) are increased in number in the INL of Math5-null retinas. Enlarged views of boxed regions are shown in A' to J'. Scale bar equals 100 μm.