Figure 4
From: MATH5 controls the acquisition of multiple retinal cell fates
The cone-bipolar fate of Math5 -lineage cells in the absence of Math5. Adult retinal sections from the control (top panels) and Math5-null (bottom panels) mice were immunolabeled with cell type-specific markers (red) and anti-GFP (green). (A-E) Compared to the control retina in which GFP expression is not co-localized with bipolar cell markers, a few of GFP+ cells in the Math5-null retina are positive for CHX10 (arrows), Goα (arrow), VSX1 (arrow) or recoverin (arrow) but not for PKCα (E). (K) Quantification of GFP+ cells expressing specific markers in the ONL, INL and the GCL per retinal section. Scale bar equals 100 μm. Notes: #For BHLHB5+, PROX1+ and ISL1+ cells in the INL, only the amacrine cells were counted per retinal section; §RXRγ+ and rhodopsin+ cells were counted per 350 μm linear length.