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Figure 3 | Molecular Brain

Figure 3

From: NMDAR2B tyrosine phosphorylation regulates anxiety-like behavior and CRF expression in the amygdala

Figure 3

Abrogation of increased anxiety-related behavior of GluN2B-YF mice by intraperitoneal injection of the CRF 1 receptor antagonist NBI 27914. The reduced time spent in the open arms shown by GluN2B-YF mice in the elevated plus-maze test (WT, n = 10; YF, n = 12; F(1,37) = 7.12, p < 0.05, two-way ANOVA/Tukey's post-hoc test) was attenuated by intraperitoneal injection of NBI 27914 (WT, n = 8; YF, n = 9; F(1,37) = 2.31, p > 0.1, two-way ANOVA/Tukey's post-hoc test). The asterisk indicates significant differences. n.s., not significant.

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