Figure 1

Effect of neuronal activity on Bdnf transcripts. All data are presented as fold changes over level of WT-Ctrl for that exon. (A). Relative expression levels of individual Bdnf transcripts at baseline (Ctrl) and after electroconvulsive shock (ECS) in the medial prefrontal cortex (mPFC) of WT and BDNF-KIV mice (n = 3 each condition). (B). Relative levels of individual Bdnf transcripts at the end of the lights on, rest cycle (Sleep) and at the end of the lights off, active cycle (Active) in WT and BDNF-KIV animals (n = 3 each group).