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Figure 2 | Molecular Brain

Figure 2

From: Opposing roles of PlexinA and PlexinB in axonal branch and varicosity formation

Figure 2

Reducing PlexinA in axons produces opposite effects from reducing PlexinB. A, The pSc axonal arbors in PlexinA mutants have significantly more branches compared to controls. RNAi of PlexinB in pSc neurons using the 455-Gal4 driver significantly reduced the number of branches compared to 455-Gal4 controls. B, PlexinA RNAi in pSc neurons increased the total axonal arbor size, and PlexinB RNAi in pSc neurons decreased the arbor size. Combining the RNAi in pSc neurons with the heterozygous mutant enhanced the RNAi phenotype compared to 455-Gal4 controls, but was not significantly different from RNAi in pSc neurons alone. 1 asterisk indicates statistically significant differences with p values less than 0.05, 2 asterisks represent p values less than 0.01, and 3 asterisks represent p values less than 0.001. Measurements in all PlexinA mutants are significantly greater than measurements in all PlexinB mutants in both graphs, and are not indicated for clarity.

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