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Table 1 Enhancers of the park-RNAi wing phenotype

From: Genome-wide screen for modifiers of Parkinson's disease genes in Drosophila

Deficiencies Breakpoints Strength of modificationa
Df(2L)net-PMF 21A1;21B7-8 ++
Df(2L)BSC28 23C5-D1;23E2 ++++
Df(2L)cl-h3 25D2-4;26B2-5 ++
Df(2L)BSC7 26D10-E1;27C1 ++
Df(2L)ED611 29B4;29C3 ++
Df(2L)BSC17 30C3-5;30F1 ++
Df(2L)Mdh 30D-30F;31F +++++
Df(2L)BSC50 30F5;31B1 ++++++
Df(2L)FCK-20 32D1;32F1-3 +++
Df(2R)nap9 42A1-2;42E6-F1 +++++
Df(2R)cn9 42E;44C ++
Df(2R)H3E1 44D1-4;44F12 +++
Df(2R)en30 48A3-4;48C6-8 +++
Df(2R)BSC39 48C5-D1;48D5-E1 ++++
Df(2R)BSC161 54B2;54B17 ++++
Df(2R)Exel7162 56F11;56F16 ++++
Df(2R)59AD 59A1-3;59D1-4 +++
Df(3L)AC1 67A2;67D11-13 +++++
Df(3L)XS533 76B4;77B ++
Df(3L)BSC249 79B2;79D2 ++
Df(3R)BSC47 83B7-C1;83C6-D1 ++
Df(3R)Tpl10 83C1-2;84B1-2 ++
Df(3R)BSC43 92F7-93A1;93B3-6 ++
Df(3R)BSC56 94E1-2;94F1-2 ++
Df(3R)BSC137 95A2-4;95A8-B1 +++
Df(3R)BSC42 98B1-2;98B3-5 ++
  1. Each deficiency was crossed into the park RNA i background and the wing posture phenotype was scored. Crosses were maintained at 29°C.
  2. a Each '+' represents 1.0 SD from the mean pentrance (i.e. ~22.4%) observed for park RNAi alone flies.