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Table 1 Enhancers of the park-RNAi wing phenotype

From: Genome-wide screen for modifiers of Parkinson's disease genes in Drosophila

Deficiencies

Breakpoints

Strength of modificationa

Df(2L)net-PMF

21A1;21B7-8

++

Df(2L)BSC28

23C5-D1;23E2

++++

Df(2L)cl-h3

25D2-4;26B2-5

++

Df(2L)BSC7

26D10-E1;27C1

++

Df(2L)ED611

29B4;29C3

++

Df(2L)BSC17

30C3-5;30F1

++

Df(2L)Mdh

30D-30F;31F

+++++

Df(2L)BSC50

30F5;31B1

++++++

Df(2L)FCK-20

32D1;32F1-3

+++

Df(2R)nap9

42A1-2;42E6-F1

+++++

Df(2R)cn9

42E;44C

++

Df(2R)H3E1

44D1-4;44F12

+++

Df(2R)en30

48A3-4;48C6-8

+++

Df(2R)BSC39

48C5-D1;48D5-E1

++++

Df(2R)BSC161

54B2;54B17

++++

Df(2R)Exel7162

56F11;56F16

++++

Df(2R)59AD

59A1-3;59D1-4

+++

Df(3L)AC1

67A2;67D11-13

+++++

Df(3L)XS533

76B4;77B

++

Df(3L)BSC249

79B2;79D2

++

Df(3R)BSC47

83B7-C1;83C6-D1

++

Df(3R)Tpl10

83C1-2;84B1-2

++

Df(3R)BSC43

92F7-93A1;93B3-6

++

Df(3R)BSC56

94E1-2;94F1-2

++

Df(3R)BSC137

95A2-4;95A8-B1

+++

Df(3R)BSC42

98B1-2;98B3-5

++

  1. Each deficiency was crossed into the park RNA i background and the wing posture phenotype was scored. Crosses were maintained at 29°C.
  2. a Each '+' represents 1.0 SD from the mean pentrance (i.e. ~22.4%) observed for park RNAi alone flies.