Figure 1
From: The dual origin of the peripheral olfactory system: placode and neural crest
Neural crest-derived cells in the embryonic olfactory epithelium. a-d, Confocal images of direct GFP fluorescence and anti-Sox10 immunostaining in the olfactory epithelium of E12.5 (a) and E14.5 (b) Wnt1-Cre/Floxed-EGFP mice and E12.5 (c) and E14.5 (d) P0-Cre/Floxed-EGFP mice reveal the presence of neural crest-derived cells in the olfactory epithelium. e, Confocal images of direct Venus fluorescence and anti-Sox10 immunostaining in the olfactory epithelium of E14.5 Sox10-Venus mice confirm the presence of neural crest-derived cells in the olfactory epithelium. Asterisks indicate the nasal cavity. Scale bars: (a, b, d) 20 μm, (c, e) 50 μm.