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Table 3 Statistical comparison of spine shape classification

From: Automated 4D analysis of dendritic spine morphology: applications to stimulus-induced spine remodeling and pharmacological rescue in a disease model

 

Stubby

Mushroom

Thin

 

Manual

Auto

Manual

Auto

Manual

Auto

Median

7.0%

13.5%

65.5%

59.4%

11.7%

9.3%

SD

±11.4

±7.1

±20.0

±10.9

±15.5

±10.1

CV

1.10

0.49

0.33

0.18

0.99

0.80

P

0.033*

0.895

0.346

  1. Dendritic spines were classified as stubby, mushroom, or thin using the manually or automatically generated geometric measurements. P: The Kolmogorov Smirnov test was used to compare the manual and automated distributions (*significant difference between the manual and automated measures).