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Figure 6 | Molecular Brain

Figure 6

From: Properties of Contextual Memory Formed in the Absence of αCaMKII Autophosphorylation

Figure 6

Contextual LTM formation after 5 conditioning trials is impaired in 18 month-old αCaMKII autophosphorylation-deficient mice. Means ± s.e.m. are shown. a: Eighteen-month-old WT mice (n = 10) and αCaMKIIT286A mutants (n = 10) were trained with five tone-shock pairings and tested for recent contextual LTM 24 hours after conditioning. The mutants showed significantly less freezing. b: The same mice as in a were tested for cued fear memory 24 hours after the context test. For both genotypes there was significant tone fear memory. **, P < 0.01.

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