Figure 2
Roles of protein synthesis and NMDAR in the hippocampus in the reconsolidation of spatial memory. (A) Experimental design. (B) Probe trial at day 3 (PT 1) [VEH, n = 9; ANI, n = 11; AP5 (1 μg/μL), n = 10; AP5 (2 μg/μL), n = 12; AP5 (4 μg/μL), n = 13]. *P < 0.05, comparisons of searching scores in the TQ vs. time spent in the other quadrants by post hoc Newman-Keuls test after significant one-way ANOVA. (C) Probe trial at day 4 (PT 2). *P < 0.05, time spent in the TQ vs. time spent in the other quadrants by post hoc Newman-Keuls test after significant one-way ANOVA. $, #P < 0.05, comparisons of searching scores in the TQ with ANI- and AP5 (4 μg/μL)-infused groups, respectively. Error bars are SEM. Time spent (s) in target (T), adjacent left (L), adjacent right (R), and opposite (O) quadrants during the probe trial is shown.