Figure 3
From: Robust spinal neuroinflammation mediates mechanical allodynia in Walker 256 induced bone cancer rats
Changes of expression of GFAP and OX-42 protein in the dorsal horn of the spinal cord detected by immunohistochemistry after the rats received carcinoma cells. (A) and (B) showing representative images for GFAP and OX-42 immunostaining respectively. (C) showing the selected area marked with red square in the spinal cord for quantification. (D, E) Quantification of astrocyte and microglia expression in the spinal dorsal horn after intra-tibial inoculation of Walker 256. Percentages of immunostaining are expressed as mean ± SEM (3 ~ 5 for each group). **p <0.01 vs. normal rats.