Figure 4
From: Robust spinal neuroinflammation mediates mechanical allodynia in Walker 256 induced bone cancer rats
Changes of inflammatory cytokines IL-1β, IL-6, TNF-α mRNA level detected by Semiquantitative RT-PCR analysis. (A) and (B) showing the mRNA levels in spinal dorsal horn 8 days and 16 days after intra-tibial inoculation of Walker 256 respectively. The relative mRNA level was expressed as a ratio relative to the normal control. *p < 0.05, **p < 0.01 vs. normal rats. (C) showing the protein level of IL-1β, IL-6, TNF-α in the spinal dorsal horn at 12 days after Walker 256 inoculation. * p < 0.05, vs. PBS rats.