Skip to main content
Figure 5 | Molecular Brain

Figure 5

From: mGluR1,5 activation improves network asynchrony and GABAergic synapse attenuation in the amygdala: implication for anxiety-like behavior in DBA/2 mice

Figure 5

Amygdala neurons in DBA/2 mice show more diversified excitability. Neuronal excitability was assessed by a gap (ΔV) between threshold potential (Vts) and resting membrane potential (Vr), in which the membrane potentials were measured by whole-cell current-clamp recording in brain slices. A) shows the measurement and assessment of neuronal excitability from the recorded sequential spikes in an amygdala neuron. B) The histogram shows the number of neurons versus ΔV, i.e., the distributions of amygdala neuron excitability, from FVB/N mice (white bars) and DBA/2 mice (gray bars). The fitting curves in bell-shape are from FVB/N mice (black line) and DBA/2 mice (gray line). The wide curve in DBA/2 mice shows a diversified excitability. C) shows the coefficients of variance (standard deviation over mean) for ΔV of all amygdala neurons in FVB/N (white bar) and DBA/2 (gray bar). D) shows the coefficients of variance for ΔV of all amygdala non-fast spiking neurons in FVB/N (white bar) and DBA/2 (gray bar). E) shows the coefficients of variance for ΔV of amygdala fast spiking neurons in FVB/N (white bar) and DBA/2 (gray bar).

Back to article page