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Table 1 Studies on signaling pathway of CREB activation by Group I mGluRs in cingulate cortex

From: Roles of CREB in the regulation of FMRP by group I metabotropic glutamate receptors in cingulate cortex

Signaling molecules

Manipulations

Effects on CREB phosphorylation induced by DHPG

References

AC1

AC1 knockout

Reduced

38

PKA

PKA inhibitor

Reduced

38

CaMKIV

CaMKIV knockout

Reduced

38

 

CaMK inhibitor

Reduced

37

 

CaMKIV over expression

Enhanced

37