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Table 1 General physical characteristics and sensory/motor functions of 1d2d-PSD-95-EGFP KI mice and their wild-type littermates

From: Impaired synaptic clustering of postsynaptic density proteins and altered signal transmission in hippocampal neurons, and disrupted learning behavior in PDZ1 and PDZ2 ligand binding-deficient PSD-95 knockin mice

  WT KI
Physical characteristics   
Weight (grams) 28.5 (± 0.8) 24.9 (± 0.5)
Rectal temperature (°C) 37.1 (± 0.2) 36.9 (± 0.2)
Grip strength 0.86 (± 0.019) 0.93 (± 0.029)
Sensory motor reflex   
Acoustic startle response (arbitrary unit)   
Stimulus intensity = 110 dB 0.9 (± 0.07) 0.5 (± 0.09)
Stimulus intensity = 120 dB 1.1 (± 0.07) 0.6 (± 0.08)
Prepulse inhibition (%; startle stimulus = 110 dB)   
Prepulse intensity = 74 dB 32.1 (± 5.2) 38.2 (± 10.2)
Prepulse intensity = 78 dB 58.4 (± 4.0) 44.9 (± 9.7)
Pain test   
Hot plate (latency; seconds) 9.2 (± 0.6) 8.9 (± 0.4)
Motor tests   
Wire hang (latency to fall; seconds) 56.4 (± 1.9) 43.6 (±5.8)
Rotarod (latency to fall; averages of three trials)   
Day 1 118.8 (± 21.0) 89.6 (± 16.2)
Day 2 183.3 (± 14.9) 151.3 (± 18.0)
  1. Data represent the mean (±SEM) (WT mice, n = 16, KI mice, n = 16).