Figure 5

NMDA/AMPA ratio in lPB-CeC and BLA-CeC synapses. A, The NMDA/AMPA ratio in naive (open bar; n = 17) and fear-conditioned (filled bar; n = 22) mice at lPB-CeC synapses. Circles indicate the individual ratio for each neuron. Sample traces of NMDA current (upper trace) and AMPA current (lower trace) are superimposed for naive (top) and FC (bottom) mice. The average of 15 consecutive waves (5 min) taken 20–25 min after CNQX application, followed by changing holding potential to Vh = +40 mV, and those taken 5 min before the application of CNQX at a holding potential of Vh = −60 mV are superimposed. B, The NMDA/AMPA ratio in naive (open bar; n = 11) and fear-conditioned (filled bar; n = 20) mice in BLA-CeC synapses. Diamonds indicate individual ratio for each neuron. Sample traces of NMDA current (upper trace) and AMPA current (lower trace) are superimposed for naive (top) and FC (bottom) mice. The average of 15 consecutive waves (5 min) taken 20–25 min after CNQX application, followed by changing holding potential to Vh = +40 mV, and those taken 5 min before the application of CNQX at a holding potential of Vh = −60 mV are superimposed.