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Figure 5 | Molecular Brain

Figure 5

From: Synaptosomal-associated protein 25 mutation induces immaturity of the dentate granule cells of adult mice

Figure 5

Rescue of the immature state of the DG and working memory deficit in SNAP-25 KI mice by valproate treatments. (A-D) Effects of chronic valproate treatment beginning on postnatal day 16 on the expression levels of calbindin, calretinin, and DCX in the DG (n = 3 mice each). (E) Effects of valproate administration on enlargement of the DG (n = 3 mice each). (F) Effects of valproate treatment on the working memory deficit in mutants (control vehicle: n = 3, control valproate: n = 8, KI vehicle: n = 3, KI valproate: n = 7).

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Molecular Brain

ISSN: 1756-6606