Figure 6
From: Regulation of epileptiform activity by two distinct subtypes of extrasynaptic GABAA receptors
THIP at low concentration has no effect on the amplitude and frequency of mIPSCs. A, B, Representative traces showing mIPSCs recorded in control and THIP (5 μM) treated neurons. Note that in the presence of THIP, baseline was always noisier than control traces, indicating the activation of extrasynaptic GABAA-Rs. C, D, No significant difference between the mIPSC amplitude (p > 0.6) and frequency (p > 0.4) in control and THIP-treated neurons.