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Figure 6 | Molecular Brain

Figure 6

From: An unexpected role of neuroligin-2 in regulating KCC2 and GABA functional switch

Figure 6

Neuroligin-2 regulates both GABAergic and glutamatergic synapse formation. A-B, Sample traces showing mIPSCs (A) and mEPSCs (B) from 10–12 DIV control and NL2shRNA-transfected neurons. C, Bar graphs showing the frequency of mIPSCs (left Y-axis) and mEPSCs (right Y-axis). n = 10 neurons per group, *p < 0.05, **p < 0.01, unpaired Student’s t-test. D-E, Sample traces showing whole-cell sodium currents (D) and potassium currents (E) in response to depolarizing voltage steps. F, I-V plot of the mean amplitude of sodium and potassium currents in control (n = 7) and NL2shRNA-transfected neurons (n = 9).

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