Table 5 MiRNAs differentially expressed in sALS and controls, and predicted recognition elements (MRE) in NFL 3′UTR
miRNA | Expression in sALS compared to controls | NFL mRNA 3′UTR target | Conservation of MREs |
|---|---|---|---|
23a | down | S/M/L | Conserved |
23b | down | S/M/L | Conserved |
30a | down | S/M/L | Conserved |
30b | down | S/M/L | Conserved |
146a* | up | M/L | Not conserved |
192 | down | M/L | Conserved |
193a-5p | down | M/L | Not conserved |
215 | down | M/L | Conserved |
524-5p | down | L | Not conserved |
556-5p | down | M/L | Not conserved |
582-3p | down | S/M/L | Not conserved |