Figure 2From: Neurological characterization of mice deficient in GSK3α highlight pleiotropic physiological functions in cognition and pathological activity as Tau kinaseBiochemical analysis of GSK3 isozymes in mouse brain extracts. Levels of total GSK3 protein, pS21/S9 and pY279/Y216 in total protein extracts from hippocampus and forebrain from AAC mice compared to control AA- mice (A) and from hippocampus and cortex from GSK3α.KO mice versus wild-type FvB mice (B). Western blots were digitally quantified, normalized for actin and reported relative to the respective control mice. Data (mean±SEM) are statistically analyzed by unpaired Student’s t-test (two-tailed), n=6 or 7 per genotype; *p<0.05, ** p<0.01, *** p<0.001, **** p<0.0001.Back to article page