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Figure 2 | Molecular Brain

Figure 2

From: Neurological characterization of mice deficient in GSK3α highlight pleiotropic physiological functions in cognition and pathological activity as Tau kinase

Figure 2

Biochemical analysis of GSK3 isozymes in mouse brain extracts. Levels of total GSK3 protein, pS21/S9 and pY279/Y216 in total protein extracts from hippocampus and forebrain from AAC mice compared to control AA- mice (A) and from hippocampus and cortex from GSK3α.KO mice versus wild-type FvB mice (B). Western blots were digitally quantified, normalized for actin and reported relative to the respective control mice. Data (mean±SEM) are statistically analyzed by unpaired Student’s t-test (two-tailed), n=6 or 7 per genotype; *p<0.05, ** p<0.01, *** p<0.001, **** p<0.0001.

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